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"Zhang, Grace Qiao"
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Request strategies: A comparative study in Mandarin Chinese and Korean
(ProQuest: ... denotes non-US-ASCII text omitted.) This study examines request strategies, detailing the relation between strategies and two social variables, Power and Distance (familiarity), in Chinese and Korean workplaces. Chapter 1 is an overview of the study: the definition of request, the motivation and purpose for the study, and the methodology using the Cross-Cultural Speech Act Realization Project (CCSARP). [...]the book offers a thorough linguistic analysis of request strategies in the Chinese and Korean work place, and promotes better understanding of cross-cultural communication. a Linguistics & TESOL, University of Texas at Arlington, Arlington, TX, 76013, USA, weiwen.lan@mavs.uta.edu.
Book Review
Request Strategies: A Comparative Study in Mandarin Chinese and Korean
Su reviews Request Strategies: A Comparative Study in Mandarin Chinese and Korean by Yong-Ju Rue and Grace Qiao Zhang.
Book Review
Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells. Owing to its high negatively charged property, heparan sulfate (HS) on the surface of host cells is used by many viruses as cofactor to facilitate viral attachment and initiate cellular entry. Therefore, inhibition of the interaction between viruses and HS could be a promising target to inhibit viral infection. In the current study, the interaction between the receptor-binding domain (RBD) of MERS-CoV and heparin was exploited to assess the inhibitory activity of various sulfated glycans such as glycosaminoglycans, marine-sourced glycans (sulfated fucans, fucosylated chondroitin sulfates, fucoidans, and rhamnan sulfate), pentosan polysulfate, and mucopolysaccharide using Surface Plasmon Resonance. We believe this study provides valuable insights for the development of sulfated glycan-based inhibitors as potential antiviral agents.
Journal Article